Linda Partridge, the founding director of Max Planck Institute of Aging, Germany, and other five authoritative scientists updated and improved the Cellular senescence logo based on the aging research in the past 10 years, and published an authoritative review of "12 aging logos" on the top scientific journal Cell, providing theoretical support for anti-aging product research and development for K2LT'S!
The field of aging research has identified 12 markers that represent common characteristics of aging in different organisms. Changing intercellular communication labels: intercellular communication capsules
Cell communication is a new field formed in the past 20 years with the development of cell biology and molecular biology, and is one of the current research hotspots in life sciences. Many of the significant technological achievements in recent years have come from this field and quickly applied to clinical practice. These achievements not only elucidate the pathogenesis of diseases, but also can be applied to diagnosis and treatment, becoming an important source of new diagnostic and treatment methods.
The results of Human genome research in the 20th century show that 20% of the 32000 genes encoding proteins are related to signal transduction. The proteins they encode include transmembrane receptors, G protein, signal generating enzymes, etc. Among them, there are more than 520 protein kinases and more than 130 reversible proteins that precisely regulate protein phosphorylation. According to different catalytic substrates, protein kinases can be divided into Tyrosine kinase or serine/Threonine kinase, and some kinases have dual activities. Up to now, there are more than 90 protein Tyrosine kinase (PTK) genes known, including 58 receptor protein Tyrosine kinase (RPTK) genes, which are divided into 20 subgroups; There are 32 cytoplasmic non receptor protein Tyrosine kinase genes, which are divided into 10 subfamilies. Among about 30 known tumor suppressor genes and over 100 oncogenes, protein kinase genes, especially PTK, account for a significant proportion. Only multicellular animals have PTK, which accounts for approximately 3% of the genome and plays an important role in the normal development of multicellular animals. The mutations in these genes have led to many cancers in humans.
Intracellular signal transduction begins with the binding of Signaling molecule (such as cytokines) to Cell surface receptor. This binding triggers a cascade reaction of specific molecular sequences downstream of the signal channel, including gene activation and subsequent protein coding. Signaling molecule are transmitted from one cell to another, that is, intercellular communication. The number of diseases related to cell communication disorder is unexpected. Tumor is a prominent example, and inflammation, autoimmune diseases and even cardiovascular diseases are also related to it. Viruses and bacteria often cause human diseases by destroying human cell communication.
The 21st century is the era of biology and information, and research on cellular communication from bacteria to humans will deepen. The research on the above-mentioned signal transduction related genes and their products has just begun, and there is great potential for theoretical and applied research. With the deepening of systematic research on Ion channel and the progress of research on other cell communication mechanisms, the essence of meridians in Chinese medical treasure house should be clarified in this century; The study of cellular communication mechanisms will gradually conquer a group of diseases of unknown causes and incurable diseases. The mass production of cytokines and their receptors provides new methods for the treatment of related diseases. The success of Tyrosine kinase inhibitor (STI571, Gleevec) in the treatment of chronic myeloid leukemia has opened up a new direction to search for disease treatment targets from the signal transduction pathway. Recently, research targeting Janus kinase 3 in the treatment of leukemia and inflammation is becoming a new hot topic.
As we age, our cells become less effective in communicating with each other. This is manifested in many aspects, including a decrease in immune system capacity and disruption of hormone levels and systemic blood factors.
Intercellular communication refers to the transmission of information from one cell through a medium to another cell to generate corresponding reactions. The signal transduction and gene expression regulation of the nervous, endocrine, and immune regulatory systems are the foundation of animal physiology and biochemistry, and the purpose of cell signal transmission is to respond and adapt to your internal and external environment. Due to their contribution to the adjustment of your body, the normal functioning of cellular signaling pathways is crucial for maintaining and enhancing health. Therefore, when the cell signal transmission pathway operates well, your body can run smoothly.
The positive effects of intercellular communication capsules lie in the adoption of technological formulas, advanced technology, quantification of natural ingredients, synergy and integrity of action, and certainty of effectiveness.
This product is composed of K2LT'S proprietary mixture ingredients, Luteolin, astragaloside A, rutin, and Quercetin. It has the functions of enhancing the immune function of the body, anti-aging, and anti fatigue. There are also anticancer cells, antiviral, antibacterial, anti-inflammatory, analgesic, which can enhance immunity, anti-tumor, and resist high uric acid.
Biological significance of cell Gap junction communication: adjacent cells can share small molecules, which can quickly and reversibly promote the Concerted reaction of adjacent cells to external signals. For example, under the action of Glucagon, hepatocytes have increased the concentration of small molecules CAMP in cells, and spread to other adjacent cells through cell Gap junction to jointly regulate the role of these cells in glucose metabolism.
The composition of intercellular communication is to communicate with the receptor through the metamorphic cell signal, so as to help the human body maintain the level of Brain-derived neurotrophic factor (BDNF), help the generation of human neurons, and help the human body form healthy cognitive function, memory, and attention.
K2 longevity technology uses high-tech means to produce this composition, which can effectively inhibit the generation of superoxide anion free radicals and Hydroxyl radical that cause aging. It is a precious and effective anti-aging drug, which can delay the passage of time, safe, reliable, and effective.
The 12 major anti-aging signs of K2 longevity technology: change of intercellular communication, Cellular senescence, runaway nutrition induction, loss of protein homeostasis, prohibition of megaautophagy, ecological imbalance, epigenetic changes, genomic instability, mitochondrial dysfunction, stem cell failure, telomere depletion, chronic inflammation; By applying cutting-edge life technology, we provide consumers with safe and efficient pure natural, anti-cell aging high-tech products, intelligent combinations, and technological formulas, significantly improving human lifespan.
K2- Longevity Technology - From cutting-edge technology in the United States